• We offer tailored partnerships to support and transform drug discovery.

    Every collaboration is a bespoke arrangement, meticulously designed to discover new compounds and targets in patient relevant disease models.

  • MIMETAS offers flexible fee-for-service solutions for therapy prioritization, optimization, and de-risking of compounds.

    As an extension of your team, MIMETAS provides the expertise and resources needed for effective research and development.

  • Our OrganoReady program is made for you when you need optimized assays for investigational toxicology.

    We guarantee OrganoReady performance according to specifications, in a fast and convenient sales transaction with a clear fee structure.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.
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Cell-Cell Interactions

Co-culture layered & structured tissues without artificial membranes
with perfect imaging, to study barrier-free cellular interactions,
cell-cell signaling, and migration.

Why cell-cell interactions?

OrganoPlate® allows you to develop a large variety of tissue- and disease models, applicable for drug testing and evaluation. Study relevant 3D tissue biology in a simple manner by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment.

We have optimized the OrganoPlate® platform to study cell-cell interaction in multiple tissue culture setups. OrganoPlate® enables you to:

  • Combine a tubular culture with cells cultured in an extracellular matrix (ECM)
  • Grow two tubules in parallel
  • Culture two or more cell types in adjacent ECM gels
  • Develop a tube-in-a-tube culture

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  • Co-culture different cell types without artificial membranes
  • Enable stratified co-cultures with relevant tissue structures
  • Study cellular interactions, cell-cell signaling, migration



  • Immunostaining for specific markers of present cell types
  • Basal lamina formation
  • Assess the influence of:
    • supporting cells in strengthening barrier tissues
    • (activated) immune cells in co-culture, for example of CNS, gut, tumor cells
    • supporting cells (for example pericytes, hepatocytes) on sprouting/angiogenesis

How to grow your 3D tissue models?

Discover with this video how to grow and study your sophisticated three-dimensional (3D) tissue models in the OrganoPlate®.

Learn more about:

  • the look and feel of OrganoPlate®
  • how the platform fits into your current workflow
  • which tissue culture possibilities are of your interest

Our Technology

Want to know more?

Get up to speed with 3D tissue culture and learn how OrganoPlate® supports your research needs.

Knowledge Center Contact us


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