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  • Technology
  • Products
    • OrganoPlate® 2-lane 96
      • Supporting up to 96 tissue models on a single plate. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the two channels of each chip.

    • OrganoPlate® 3-lane 40
      • Supporting up to 40 tissue models on a single plate. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the three channels of each chip.
    • OrganoPlate® 3-lane 64
      • Supporting up to 64 tissue models on a single plate. Specially designed for automated workflows. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the three channels of each chip.
    • OrganoPlate® Graft
      • The first in vitro tissue culture platform that allows co-culture of spheroids, organoids, and tumors with a perfused microvascular bed and vascularization of 3D tissues.

    • OrganoReady® Caco-2
      • Offering 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies.
    • OrganoFlow®
      • Driving precisely-controlled perfusion flow in the OrganoPlate® platform
    • OrganoTEER®
      • Enabling fast, automated, and impedance-based TEER measurements in OrganoPlate®. Assay 40 tissue culture chips with a few clicks, in less than one minute.
    • Workshops & Trainings
      • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
    • All Products
      • OrganoPlate® is the solution for all in vitro tissue culture applications. Explore the entire OrganoPlate® family and its dedicated instruments here.

  • Services
    • Compound profiling & Screening
      • Get robust compound data in human tissue models. With proven pheno­typic assays in the OrganoPlate® platform, we support your drug discovery and development needs.
    • Custom Model & Assay Development
      • We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.
    • Drug Development Partnerships
      • Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.
    • All Services
      • We offer several services to support your drug discovery and development needs. Find the overview here.
  • Applications
    • Perfused Tubules
      • Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.

    • Cell-Cell Interactions
      • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

    • 3D Cell Migration
      • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

    • Angiogenesis
      • Membrane-free microvascular formation and growth through an extracellular matrix (ECM).

    • Vascularization
      • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

    • All Applications
      • OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.

  • Resources & Support
    • Knowledge Center
      • Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs.

        Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, by our scientists.

    • Publications
      • Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.

    • Case Studies
      • Get inspired by research done by our scientists, partners, and customers around the globe.

    • Blogs
      • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
    • Workshops & Trainings
      • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
    • Technical Support
      • Any support questions about purchasing, products, or 3D tissue culture and analysis? Get in touch with our experts.
    • Request a quote
      • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

    • FAQ
      • Frequently asked questions answered by our experts. Find here the answer you're looking for.
  • About Mimetas
  • Supporting up to 96 tissue models on a single plate. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the two channels of each chip.

  • Supporting up to 40 tissue models on a single plate. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the three channels of each chip.
  • Supporting up to 64 tissue models on a single plate. Specially designed for automated workflows. Its unique PhaseGuide™ technology enables cells to interact and migrate freely between the three channels of each chip.
  • The first in vitro tissue culture platform that allows co-culture of spheroids, organoids, and tumors with a perfused microvascular bed and vascularization of 3D tissues.

  • Offering 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies.
  • Driving precisely-controlled perfusion flow in the OrganoPlate® platform
  • Enabling fast, automated, and impedance-based TEER measurements in OrganoPlate®. Assay 40 tissue culture chips with a few clicks, in less than one minute.
  • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
  • OrganoPlate® is the solution for all in vitro tissue culture applications. Explore the entire OrganoPlate® family and its dedicated instruments here.

  • Get robust compound data in human tissue models. With proven pheno­typic assays in the OrganoPlate® platform, we support your drug discovery and development needs.
  • We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.
  • Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.
  • We offer several services to support your drug discovery and development needs. Find the overview here.
  • Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.

  • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

  • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

  • Membrane-free microvascular formation and growth through an extracellular matrix (ECM).

  • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

  • OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.

  • Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs.

    Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, by our scientists.

  • Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.

  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
  • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
  • Any support questions about purchasing, products, or 3D tissue culture and analysis? Get in touch with our experts.
  • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

  • Frequently asked questions answered by our experts. Find here the answer you're looking for.
  • Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.
ENGLISH

Bas Trietsch

 

This interview is part of a series of conversations with the people working at Mimetas. The 'I' in Mimetas focuses on the personal side of the scientists that drive our world. Today we have a chat with Bas Trietsch, Chief Technology Officer and straight shooter at Mimetas.

How would you describe your job to me, if I were 5 years old?

At Mimetas, I work on developing and inventing new versions of the OrganoPlate®. I also ensure that the current OrganoPlates are made correctly and are available to everybody. When a client, or a biologist from our Model Development, asks for a specific new feature for the OrganoPlate, we get to work. I also work together with our factory, making sure that production is efficient and reliable.

What does an average day for you look like working at Mimetas?

My days during the week are quite diverse. One day in the week I reserve to spend at the factory, where I work with the guys at our factory to look at any issue in production. We also look at opportunities to increase production and quality. Two days in the week I schedule most of the meetings with my team, which means talking a lot with the colleagues running our different projects. The remaining two days I spend working with suppliers and talking to different parts of the company to ensure everybody has what they need. During those days I also brainstorm with our biologists to solve a particular need for their projects. That starts a complete development process, from brainstorming, to prototype development, to picking the best concept, to developing the project.

What is your favorite pastime?

I like cooking a lot! I like good food and wine, but I also like making it. So with summertime arriving, I try to take some time to prepare nice food on the barbeque or on the smoker, which I recently built. I stole a drum from our factory and cut it open. After that, I burnt the inside to prepare the drum for smoking. Other than that I like traveling, snowboarding, and diving. I went diving in Australia and Egypt, but I’m afraid Egypt has ruined me forever – it’s just so beautiful.

Is it better to be perfect and late, or good and on time?

Good and on time is better. My girlfriend is a trauma surgeon, which means that time is crucial. They have a saying, “better is the enemy of good”. When developing a product, it means that if you keep fiddling around, you sometimes make it worse than before. That’s especially true when time is a big factor. In our case, the competition is not sitting still. So this is a big challenge in product development: when is it good enough? There are always things to improve, tweak, and tune. That also means that your clients are waiting on the product as well. Being efficient is very important, don’t get stuck in the details. That’s why prototypes are usually not far from the finished product.

Do you prefer people being straightforward to you, or people tempering their words?

Always straightforward. I dislike it when people tip-toe around a subject, resulting in them saying “yes” when they are thinking “no”. People need to be straightforward. If I say something that is wrong, everybody in the room can call me out on it. People should be able to say what they want, which is, I think, a big strength of the Netherlands.

What small things in life make you happy?

As I said, my girlfriend is a trauma surgeon, which means she has to wake up very early. I get up with and break the morning with her. After that, I get to sleep some more, and that is such a good feeling. It is a great way to start the day.

What is your favorite quote, song, or belief, anything that you live by?

One of the things is the whole idea that you should never try to shine brighter yourself by diminishing other people. You can usually shine a lot more by letting other people shine. I think that’s true in your social life, but also in your professional life. It’s more rewarding and more productive to try to enable other people to do the best they can than to put yourself forward. There’s no culture at Mimetas to outcompete amongst ourselves, rather we try to help each other as a team. That is one of the most important things for a person, but that gets enhanced in a team.