Case Studies
Get inspired by research done by our scientists, partners, and customers around the globe. Select your topic of interest, and learn more.
3D intestine-on-a-chip model to study IBD
Together with Philip Morris International (PMI) we developed a 3D in vitro intestinal model consisting of epithelial and immune competent cells to study the hallmarks of IBD.
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3D immune cell migration towards a tumor microenvironment
We developed a 3D immune cell migration model to better understand the behavior of T cells in a tumor microenvironment.
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Antibody transcytosis across the blood-brain barrier (BBB)
We developed a unique 3D and membrane-free BBB-on-a-chip model compromising human brain endothelial cells, astrocytes, and pericytes. The model allows studying barrier function and antibody transcytosis in high-throughput.
3D pancreas model to capture intratumoral pressure
Together with Leiden Academic Centre for Drug Research (LACDR), we developed a 3D microfluidic interstitial flow model to capture the intratumoral pressure in PDAC.
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3D glomerular filtration barrier model
Researchers from Children’s Hospital Los Angeles (CHLA) developed a glomerulus-on-a-chip model to recapitulate the human glomerular filtration barrier. The model is composed of human podocytes and human glomerular endothelial cells.
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Robust angiogenesis inhibition assay
Together with researchers from LUMC, Leiden University, and Ncardia, we developed a phenotypic angiogenesis inhibition assay including endothelial cells (ECs) from induced pluripotent stem cells (iPSC).
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