On-Demand Webinar
Creating an in vitro model of the BBB does not have to be complicated. In this webinar, you will learn how you can easily create a reliable and physiologically relevant model of the BBB in OrganoPlate®. This system is successfully used by the top 10 big pharma and hundreds of academic researchers worldwide.
What you will learn
- Limitations of current in vitro BBB systems and how to overcome
- How to build a leak-tight 3D in vitro BBB model thanks to flow and co-cultures
- How to easily assess BBB permeability, integrity, and expression of transporters on the model
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How to obtain consistent and reproducible data
What others have said about the OrganoPlate®
“With the OrganoPlate by MIMETAS, we developed a 3D brain-on-a-chip model that made it easy to do high-throughput and high-content imaging to evaluate the acute toxicity of neurotoxins. OrganoPlate allowed the study of membrane-free vascular formation in a dynamic environment and further provided reliable and repeatable experiments with strong imaging capability.” — Dr. Yeoheung Yun, Associate Professor at North Carolina A&T State University
“Often you have to compromise: it’s either the throughput or it’s the complexity of the model. Getting both in the same platform…no other platforms can do that!” – Senior Scientist from top pharma
Related publications
- Wevers, N.R., Kasi, D.G., Gray, T. et al., Fluids Barriers CNS (2018) 15:23 https://doi.org/10.1186/s12987-018-0108-3
- Koo, Y., Hawkins, B.T. & Yun, Y., Scientific Reports (2018) 8:2841 https://doi.org/10.1038/s41598-018-20876-2
