OrganoReady® Blood-brain-barrier HBMEC
40 or 64 ready-to-use primary human microvasculature endothelial cell tubules for drug exposure, transport, and permeability studies.
Do you want to perform experiments in human-relevant and reproducible Blood-Brain Barrier 3D models, but don’t have the time to optimize the conditions? With the OrganoReady® BBB HBMEC, you can study the BBB like never before. In contrast to other cell lines or iPSC-based BBB models, this platform is made with primary HBMEC cells that expresses all relevant markers, transporters, receptors and enzymes.
Built on the OrganoPlate® 3-lane 40 or 64, you can immediately de-risk your compounds toxicity by measuring barrier integrity with fluorescent dye leakage, or in a faster, more sensitive method with the OrganoTEER®.
OrganoReady® BBB HBMEC features:
- 40, or 64 ready-to use HBMEC perfused tubules
- OrganoMedium HBMEC-BM
- HBMEC cell line: Human Brain Microvascular Endothelial Cells
- ECM: Collagen-I (Rat Tail)
Assess the permeability and active transport of your compounds with direct apical and basal access. Add your neuronal component to obtain a complete neurovascular unit in an optimized, and consistent batch of human primary Blood-Brain Barrier cells grown against a validated batch of Collagen-I.