• We offer tailored partnerships to support and transform drug discovery.

    Every collaboration is a bespoke arrangement, meticulously designed to discover new compounds and targets in patient relevant disease models.

  • MIMETAS offers flexible fee-for-service solutions for therapy prioritization, optimization, and de-risking of compounds.

    As an extension of your team, MIMETAS provides the expertise and resources needed for effective research and development.

  • Our OrganoReady program is made for you when you need optimized assays for investigational toxicology.

    We guarantee OrganoReady performance according to specifications, in a fast and convenient sales transaction with a clear fee structure.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.

  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.
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Advancing Preclinical Predictivity

At MIMETAS, we disrupt the approach to preclinical research. Our human organ models empower pharmaceutical researchers in the fields of toxicology and ADME, enabling expedited safety and efficacy assessments of compounds.

3D Tissue Models for Precise Preclinical Toxicology

Unlocking the secrets of human physiology has long been a challenge in toxicity studies. However, our revolutionary technology now provides a breakthrough solution. By harnessing advanced human tissue and disease models with diverse quantitative assessments, researchers can delve into drug-induced toxicity with unparalleled relevance to human physiology for efficient risk management strategy. Unmanageable toxicity accounts for 30% of clinical drug development failures, primarily attributed to the limitation of traditional models in accurately reflecting human physiology.


Speak With an Expert

Revolutionizing Toxicology

Get Inspired

Researchers from the Swiss Institute of Allergy and Asthma Research (SIAF) recently used the OrganoReady® Colon Caco-2 and OrganoReady® Colon Organoid to assess the impact of common household dishwashing detergents and rinse aids as well as food emulsifiers on potential harmful effects of these compounds on gastrointestinal health.

Food emulsifier paper

Dishwashing detergent paper

Investigative Toxicology

Our models recreate the intricate cellular interactions of human organs, enabling researchers to unravel the mechanisms behind adverse effects, study dose-response relationships, and gain deeper insights into complex toxicological pathways.

 

Predictive Toxicology

We offer the unprecedented opportunity to forecast potential toxicity outcomes, aiding in early-stage compound screening, reducing animal testing, and expediting regulatory approval

Comprehensive ADME and PK/PD Insights

Our advanced 3D models redefine ADME (Absorption, Distribution, Metabolism, and Excretion) research by replicating intricate organ interactions with unprecedented human relevance. With unparalleled precision, we unravel a drug's journey within the body, offering insights into:

  • Bioavailability
  • Tissue accumulation
  • Metabolic stability
  • Potential pharmacokinetic and pharmacodynamic interactions

Harnessing these dynamic insights allows for informed decisions in drug development, optimized dosing regimens, and an accelerated pipeline to safer, more effective pharmaceutical solutions.

 

Get inspired

A 3D Human Blood-Brain Barrier Model to Study Small Molecule Transport

Our blood-brain barrier (BBB) model offers a complex system for small molecule transport assessment. Displaying phyiologically relevant junction and transporter expression profiles, our BBB model enables the study of barrier function and antibody transcytosis in high-throughput.


Read the case study

Explore Our OrganoReady® Models:

  • OrganoReady Blood Vessel HUVEC
    Study drug distribution and vascular effects for improved pharmacokinetic evaluations, facilitating targeted drug delivery to specific tissues.
  • OrganoReady Collagen
    Pre-seeded with Collagen-I for faster, and more flexible workflow. Expand your screening capabilities and build more robust 3D in vitro cell models with the flexibility and speed of 2D models.

 

The OrganoReady Models




A colon organoid tubular structure with cellular polarization with an immunofluorescence staining of the tight junction Occludin (green) and cell nuclei (blue). This model is available with OrganoReady Colon Organoid.

Commitment to Ethical Excellence

At MIMETAS, ethics and innovation go hand in hand. We are proud to contribute to the replacement, reduction, and refinement of animal use in research. By providing an alternative to animal models, we enable safer, more effective, and ethical research that translates to human biology. Our approach aligns seamlessly with the championing innovation while prioritizing patient safety and sustainable practices.

Pioneering Organ-on-a-Chip Expertise

 

Embrace the Future of Drug Development with MIMETAS - Collaborate with us today to redefine pharmaceutical possibilities, drive meaningful progress, and enhance patient care through our advanced organ-on-a-chip technology. Together, we can shape a brighter, more sustainable future for healthcare worldwide.

If you are interested in exploring potential partnership opportunities or learning more about our ongoing projects, please contact us.


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