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      • Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.
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      • We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.
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      • Get robust compound data in human tissue models through our services. With proven pheno­typic assays in the OrganoPlate® platform, we support your drug discovery and development needs.
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      • We offer several services to support your drug discovery and development needs. Find the overview here.
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    • Perfused Tubules
      • Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.

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      • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

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      • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

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      • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

    • All Applications
      • OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.

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        Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, by our scientists.

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      • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
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  • Knowledge Center
  • About Mimetas
  • Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.
  • We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.
  • Get robust compound data in human tissue models through our services. With proven pheno­typic assays in the OrganoPlate® platform, we support your drug discovery and development needs.
  • We offer several services to support your drug discovery and development needs. Find the overview here.
  • Start today with 3D tissue modeling
    Kickstart your first experiments with the OrganoPlate® through our OrganoStart packages.
  • OrganoFlow®
    Driving precisely-controlled perfusion flow in the OrganoPlate® platform

  • OrganoTEER®
    Enabling fast, automated, and impedance-based TEER measurements in OrganoPlate®. Assay 40 or 64 tissue culture chips with a few clicks, in less than two minutes.

  • Start today with 3D tissue modeling
    Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
  • OrganoPlate® is the solution for all in vitro tissue culture applications. Explore the entire OrganoPlate® family and its dedicated instruments here.

  • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

  • Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.

  • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

  • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

  • Membrane-free microvascular formation and growth through an extracellular matrix (ECM).

  • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

  • OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.

  • Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs.

    Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, by our scientists.

  • Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.

  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
  • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
  • Any support questions about purchasing, products, or 3D tissue culture and analysis? Get in touch with our experts.
  • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

  • Frequently asked questions answered by our experts. Find here the answer you're looking for.
  • Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.
EN

OrganoReady® Organoid

40 or 64 ready-to-use adult stem cell (ASC)-derived organoid tubules for drug exposure, transport, and permeability studies.

Are you interested in dose dependent barrier disruption, and rescue? With the OrganoReady Organoid line, organoids are grown into the OrganoPlate platform as leak tight tubules, allowing you to measure drugs absorption, metabolism and impact on cell health the minute it reaches your lab. Combined with high resolution, quantitative, live microscopy techniques, these cultures require no further optimization.

Our organoid models are derived from adult stem cells (ASCs) whilst most other organoid technologies use embryonic or primary cells. This is a key distinction, as ASC-derived organoids do not require reprogramming or transformation of stem cells. The original properties of the donor, including specific disease aspects, are maintained when cultured outside of the human body. The regenerative capacity of patient-derived ASCs can therefore be utilized to reproduce organ functionality in the lab.



Early Access Program
We offer selected users two fully optimized OrganoReady Organoid models, which are compatible with high throughput screening:

  • The first proliferative organoid-based colon tubules on the market, developed as the next generation platform to characterize the mechanistic toxicology of drugs, or pollutants known to specifically affect this tissue.
  • The first proliferative organoid-based kidney tubules that can be used, for example, to evaluate drug-induced kidney injury in a more translatable way.

Given the more physiological nature of both colon and kidney tubuloids compared to cell lines, primary tissue or iPSC-derived cells, these tubules are the ideal model to not only dissect the mechanistic toxicity of small or large molecules, but also assess their adsorption, metabolism and secretion.

OrganoReady® Organoid package features:

  • 40 or 64 ready-to use ASC-derived perfused organoid tubules
  • Recovery Medium and Culture medium
  • ECM: Optimized Collagen-I (Rat Tail)

Product details

Meet the OrganoReady Organoid line

Ready-to-assay organoid tubules
40 or 64 ready-to-use kidney and colon organoid tubules seeded against collagen I, allowing you to perform assays right away.

Tailored ASC-derived organoid models
Development of other organoid models such as the small intestine or lung are in the pipeline, with any other tubules requested also at our fingertips. We source any type of epithelial tissue you need. Get in touch to learn more.

Apical and basal access
Polarized and perfused organoid tubules that allow barrier integrity (TEER), transporter, toxicity and permeability assays.

We create the model, so you can focus on your assays
Preparation and QC of OrganoReady Organoids are done by our experts. Use the OrganoReady Organoid models directly after arrival for up to 7 days.

True platform personalization
The first truly personalized ASC-derived Organoid based platform, with all tissue sourced directly from tissue donors and then optimized them to grow into our platform by our scientists.

Early access Kidney and Colon organoids now available.

Contact us

Want to know more?


Get up to speed with 3D tissue culture and learn how OrganoPlate® supports your research needs.

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