3D Human Liver Models

MIMETAS’ perfused human liver models replicate essential liver biology by integrating perfused liver vasculature with hepatocytes, Kupffer cells, and stellate cells.

This liver model is used for Drug Metabolism, Toxicity Screening, and Disease Modeling at scale.

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Hepatic Complexity Tailored to Your Research

Our liver model mimics native liver architecture, cell diversity, and perfused vasculature to support metabolization, disease modeling, and gene delivery studies in a human context.

Available Model Configurations:
Primary hepatocytes with Kupffer, stellate, and endothelial cells
Perfusable liver vasculature via lateral endothelial tubes
Polarized hepatocyte layers with bile canaliculi
Custom co-cultures and immune integrations available

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A Range of Applications

Screening for Drug-Induced Liver Injury (DILI)
AAV-mediated gene therapy delivery
Modeling steatosis, fibrosis, and MASH/MAFLD
Liver-specific disease mechanism research
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