Immunology Drug Discovery
MIMETAS offers immune-competent 3D models that deliver unprecedented insights into immune-tissue interactions.
Our platform helps researchers evaluate immune cell activation, trafficking, barrier disruption, and inflammation in physiologically meaningful environments – bridging the translational gap between preclinical studies and clinical outcomes.
Modeling the Human Immune System in vitro
Our organ-on-a-chip platform supports immune-relevant drug discovery across tissues such as gut, kidney, brain, and vasculature.
- Perfused vasculature
- Immune cell migration and extravasation
- Innate and adaptive immune cells (e.g., T cells, macrophages, dendritic cells)
- Epithelial barriers & connective tissue
- Antibodies, cytokines, and the complement system
Together, these features provide a high-fidelity platform for studying immune response, barrier function, and therapeutic activity in complex tissue environments.
Targeting Key Mechanisms That Drive Immune-Related Diseases
MIMETAS offers assays that reflect the complex biology of immune-related diseases – capturing key tissue-immune interactions in systems designed for predictive data that enables decision-making. Explore some of our example applications below and let’s talk about how we can support your research goals.
Vascular Inflammation & Immune Cell Extravasation
Chronic Kidney Disease (CKD)
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Inflammatory Bowel Disease (IBD)
Custom Immune-Competent Model Development
We collaborate with your team to incorporate defined immune cell types – whether patient-derived, engineered, or donor-matched – into compatible tissue models. Whether you're focused on mucosal immunity, myeloid activation, or lymphocyte function, let’s explore whether our platform fits your study needs.
We also support:
- Matching immune and tissue donor backgrounds
- Cytokine profiling, flow cytometry, and multiplex analytics
- Flexible scale-up for screening and optimization
