Perfused 3D Human Kidney Models
MIMETAS kidney models comprise the proximal and distal tubule, as well as the glomerulus.
Built on best-in-class adult stem cell derived organoids, MIMETAS supplements its kidney models with perfused vasculature and immune cells to study chronic kidney disease, transport and toxicity.
Kidney Complexity Tailored to Your Research Question
MIMETAS offers patient-derived adult stem cell tubular models that can be differentiated into proximal or distal states. These perfused models can include vasculature and immune cells. MIMETAS also provides glomerulus models with primary podocytes and glomerular endothelium.
Available Model Configurations:
Perfused epithelia (adult stem cell derived tubuloids, proximal/distal, RPTECs)
Immune-inclusive co-cultures: human monocyte integration (donor-specific immune cells)
Immune-stimulated inflammation using complement-activated serum
Stromal support components (e.g. fibroblasts or pericytes to mimic the kidney interstitial microenvironment)
Glomerular models based on primary podocytes and glomerular endothelium
Get Started
We are here to support you with our CRO services. Contact us to discuss your requirements.
A Range of Applications
.svg){kind=icon}
Disease modeling e.g. chronic inflammation
Renal toxicity profiling
Compound absorption and epithelial transport
Immune interaction and monocyte tracking
Selected Resources
%20--%20these%20two%20images%20should%20be%20side%20by%20side.avif)
