Perfusable vascular networks are essential for studying disease mechanisms, drug responses, and tissue engineering. Traditional vascular models lack stability and scalability, limiting their use in disease research and drug testing. Our pumpless, unidirectional microfluidic system enables long-term perfusable vascular networks, ideal for studying vascular biology, inflammation, and drug responses.This platform maintains vascular integrity for over a month, supports immune cell perfusion, and is high-throughput compatible, making it a powerful tool for advanced research.Key Features of the TechnologyLong-term vascular stability – Maintains perfusability for over one monthPumpless, unidirectional flow – Eliminates the need for external pumps and tubingScalable platform – Supports 32 vascularized microfluidic chips per plateHigh-throughput imaging compatibility – Automatable for large-scale experimentsSupports immune cell perfusion – Enables disease modeling and drug discovery