Studying pulmonary fibrosis and lung disease is challenging due to the lack of realistic preclinical models. Our Airway-on-a-Chip (AoC) system replicates the human airway microenvironment, integrating unidirectional flow, perfusable microvascular networks, and differentiated epithelium for high-throughput drug testing and disease modeling.
This innovative model captures fibrotic remodeling, inflammation, and vascular interactions, making it a powerful tool for respiratory drug discovery.
Key Features of the Model
- Unidirectional, gravity-driven flow for realistic airway fluid dynamics
- Perfusable microvascular networks for vascular-lung interactions
- Ciliated & basal epithelial cells with mucus production for physiological relevance
- High-throughput scalability, enabling parallel culture of 32 airway models
Download the poster to explore how this model is enhancing pulmonary research.
