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App Note: Investigating the hallmarks of inflammatory bowel disease (IBD) in a 3D perfused multicellular intestine-on-a-chip model

Inflammatory Bowel Disease (IBD) is multifactorial disease. Studying the underlying, biological mechanisms remains challenging due to the lack of physiologically relevant in vitro models and limited understanding pathology. In this app note, find out how we used a perfused 3D multicellular intestine-on-a-chip to study this complex disease.

Benefits of this model:

  • A robust and high throughput intestine-on-a-chip model of which the biological complexity can be tailored to a specific research question;
  • Induction and prevention of cytokine-induced intestinal inflammation;
  • Suitable for studying intestinal inflammation or screening anti-inflammatory compounds.

Learn more about this model in the application note!

 

 

 

Download the app note here

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