• We offer tailored partnerships to support and transform drug discovery.

    Every collaboration is a bespoke arrangement, meticulously designed to discover new compounds and targets in patient relevant disease models.

  • MIMETAS offers flexible fee-for-service solutions for therapy prioritization, optimization, and de-risking of compounds.

    As an extension of your team, MIMETAS provides the expertise and resources needed for effective research and development.

  • Our OrganoReady program is made for you when you need optimized assays for investigational toxicology.

    We guarantee OrganoReady performance according to specifications, in a fast and convenient sales transaction with a clear fee structure.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.

  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.
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App Note: Investigating the hallmarks of inflammatory bowel disease (IBD) in a 3D perfused multicellular intestine-on-a-chip model

Inflammatory Bowel Disease (IBD) is multifactorial disease. Studying the underlying, biological mechanisms remains challenging due to the lack of physiologically relevant in vitro models and limited understanding pathology. In this app note, find out how we used a perfused 3D multicellular intestine-on-a-chip to study this complex disease.

Benefits of this model:

  • A robust and high throughput intestine-on-a-chip model of which the biological complexity can be tailored to a specific research question;
  • Induction and prevention of cytokine-induced intestinal inflammation;
  • Suitable for studying intestinal inflammation or screening anti-inflammatory compounds.

Learn more about this model in the application note!

 

 

 

Download the app note here

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