A compromised intestinal epithelial barrier can trigger local and systemic inflammation, contributing to pathologies such as inflammatory bowel disease and celiac disease. Intestinal microbiota plays a key part in maintaining intestinal homeostasis. To further preserve the epithelial barrier in the gut, probiotics are being developed, yet their validation and selection require more suitable and human-relevant in vitro models.

Watch our on-demand webinar with our speaker Ilia Belotserkovsky, PhD on a gut-on-a-chip model in the OrganoPlate™ platform, used as a screening tool for probiotics and live biotherapeutics with homeostatic and immunomodulatory properties.

Webinar highlights:

- Using the OrganoPlate Platform to study inflammation and epithelial barrier damage  

- Inducing inflammatory processes in the model with inclusion of immune cells  

- Testing live probiotics and/or their postbiotics for immunomodulatory or homeostatic potential in a high throughput