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  • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

  • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

  • Membrane-free microvascular formation and growth through an extracellular matrix (ECM).

  • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

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  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
  • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
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EN

MIMETAS appoints Patrice Denèfle as Scientific Advisor

Patrice brings over 35 years of experience in pharmaceutical and biotechnology companies

Leiden, April 22, 2021 - MIMETAS, the global leader in organ-on-a-chip-based disease modeling, is happy to announce the appointment of Patrice Denèfle as their Scientific Advisor. Patrice brings in longstanding scientific expertise and an extensive network in the pharmaceutical industry. His involvement will support the therapeutic research strategy and spark new collaborations with leading pharmaceutical companies based on MIMETAS’ phenotypic modeling and screening capabilities.

Having authored more than 150 scientific papers and patents, Patrice has an outstanding scientific reputation and brings with him over 35 years of experience in large pharmaceutical and biotechnology companies. “As we still do not fully understand the biological mechanisms of most diseases, we need to start embracing this complexity by using appropriate translational models. MIMETAS is perfectly positioned to bring this paradigm shift to the drug development process,” according to Patrice Denèfle.

The appointment of Patrice comes at a time of rapid progress at MIMETAS. Besides offering products and services on the OrganoPlate® platform, MIMETAS is now engaging in partnerships towards joint drug development.

“I am very excited to join MIMETAS at this transformative stage.”, adds Patrice Denèfle. “I am impressed by their track record with pharma and their phenotypic screening capabilities. I am looking forward to supporting the team with developing therapies against the unsolved diseases.”

“We are thrilled to have Patrice on board as a Scientific Advisor.”, comments CEO Jos Joore. “He brings tremendous scientific knowledge and shares our vision of bringing back the human disease phenotype throughout drug development. His outstanding international network will help us to forge new collaborations that will ultimately bring urgently needed therapeutic benefits to patients.”

About Patrice Denèfle

Patrice Denèfle has played multiple key roles in drug discovery research towards new applications for patients. Among others, he served as General Manager of the Roche Institute for Research and Translational Medicine, Director of the functional genomics department at Sanofi Aventis, VP of the Digital & Translational Sciences platform Ipsen, and CSO and head of translational R&D at Genethon. He holds a Ph.D. in Biotechnology from Institut Pasteur and University Paris VII and obtained an MBA from INSEAD-CEDEP. Patrice is an author of over 150 scientific papers and patents.


Go to the official press release

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