• We offer tailored partnerships to support and transform drug discovery.

    Every collaboration is a bespoke arrangement, meticulously designed to discover new compounds and targets in patient relevant disease models.

  • MIMETAS offers flexible fee-for-service solutions for therapy prioritization, optimization, and de-risking of compounds.

    As an extension of your team, MIMETAS provides the expertise and resources needed for effective research and development.

  • Our OrganoReady program is made for you when you need optimized assays for investigational toxicology.

    We guarantee OrganoReady performance according to specifications, in a fast and convenient sales transaction with a clear fee structure.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
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An intestine-on-a-chip model of plug-and-play modularity to study inflammatory processes

On-demand Webinar

The development of drugs for the treatment of intestinal inflammatory conditions remains difficult due to the lack of reliable, robust, and high throughput in vitro models. Current models lack physiological relevance because they do not recapitulate key aspects of the intestine. Organ-on-a-chip technology can be utilized as a solution to this issue by modeling tissues in 3D to more closely resemble in vivo conditions. In this webinar, Linda Gijzen will discuss the development of a complex co-cultured organ-on-a-chip model to study the inflamed intestine.

The model contains multiple intestinal and immune cell types to increase physiological relevance. With the use of this model, biological modularity was achieved, representing key aspects of the inflamed intestine. This platform is compatible with high throughput, robust assays in which complexity that can be tailored to serve all preclinical stages in the drug discovery process.

In this webinar, you will learn:

  • How to develop an intestine-on-a-chip model in the OrganoPlate®
  • How to measure intestinal inflammation using high throughput TEER measurements
  • How to verify the physiological relevance of your 3D tissue model

Register Here


Linda Gijzen, Scientific Project Lead at MIMETAS
Linda completed her Master’s degree in biomedical sciences, specializing in toxicology and human pathobiology in 2016 and is currently working as a Scientific Project Lead at MIMETAS. In this role, she is involved in the development and characterization of 3D human based microfluidic models of the kidney, intestine, heart, and immune oncology. Besides her position as Scientific Project Lead, she is doing a Ph.D. at Mimetas and the University of Utrecht focusing on microfluidic disease models of the kidney and intestine.

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