On-demand Webinar
Chronic kidney disease (CKD) and other renal disorders impact more than 10% of the world population worldwide, posing a growing public health burden with limited treatment options and a notable lack of targeted therapies. Despite significant research efforts, the translation of preclinical findings into effective clinical treatments remains a major hurdle. New Approach Methodologies (NAMs), such as complex 3D in vitro models, offer more predictive and mechanistic insights into kidney function, disease progression, and drug response. By replicating human-relevant renal physiology and integrating key components like the immune system, NAMs may bridge the translational gap between preclinical findings and effective treatments.
Watch our on-demand webinar with Linda Gijzen (Scientific Project Lead, MIMETAS) to discover how human-relevant 3D in vitro models are advancing renal research and accelerating the development of novel, targeted therapies for diseases such as CKD.
Webinar highlights:
- Latest advances in 3D human kidney models using the OrganoPlate® with integrated immune components such as monocytes, macrophages and T cells, and mechanistic insights into renal function and pathology.
- Applications in drug development, including toxicity screening, target discovery/ validation, as well as testing of novel compounds.
- Case study about a complex kidney-on-a-chip model that captures immune interactions relevant to renal inflammation, including testing novel immunomodulant therapeutics to study drug response.
Access the recording here!