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  • About Mimetas
  • Start today with 3D tissue modeling>
    Kickstart successfully your first experiments with the OrganoPlate® through our OrganoStart packages.
  • OrganoFlow® >
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  • Start today with 3D tissue modeling>
    Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
  • OrganoPlate® is the solution for all in vitro tissue culture applications. Explore the entire OrganoPlate® family and its dedicated instruments here.

  • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

  • Get robust compound data in human tissue models through our OrganoServices. With proven pheno­typic assays in the OrganoPlate® platform, we support your drug discovery and development needs.
  • We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.
  • Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.
  • We offer several services to support your drug discovery and development needs. Find the overview here.
  • Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.

  • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

  • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

  • Membrane-free microvascular formation and growth through an extracellular matrix (ECM).

  • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

  • OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.

  • Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs.

    Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, by our scientists.

  • Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.

  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
  • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
  • Any support questions about purchasing, products, or 3D tissue culture and analysis? Get in touch with our experts.
  • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

  • Frequently asked questions answered by our experts. Find here the answer you're looking for.
  • Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.
EN

MIMETAS in consortium to develop in vitro placenta models

The most important organ in the human body

March 17, 2018 – MIMETAS is part of a consortium to develop in vitro placenta models. The objective of the iPlacenta project is to develop state-of-the-art models to mimic the placenta in vitro. This Huffington Post article stresses the importance of modeling what is probably the most important organ in the human body, giving life to us all.

The placenta rapidly develops throughout gestation and is a unique organ getting blood supply from both the mother and the child. It is made up of maternal and fetal vessels, with numerous highly branched villi lined with trophoblasts that facilitate gas, nutrient, and waste exchange.

Placenta-on-a-Chip

MIMETAS' OrganoPlate® technology offers unique functionalities, not possible with conventional 2D or 3D culture, allowing to better replicate the complex placenta tissue architecture. Currently, tissue culture using explants from the delivered placenta offers the only routine method to study the whole multicellular placenta ex vivo. This restricts our ability to understand the dynamic cellular interaction in normal and diseased placenta, since the explants are from delivered term placenta and are no longer under the same haemodynamic forces. Additionally, human tissues have to be obtained straight from delivery, limiting the availability and reproducibility.

The aim of the project is to develop a placenta-on-a-chip model and validate it in different labs. Within the project, young EU scientists will benefit from training in this rapidly growing field.

Partners and funding

Partners in the project are: Aston University, St Georges Hospital (UK), INSERM (FR), Katholieke Universiteit Leuven (BE), University College Cork (IE), University of Rostock (GER), University Hospital of Valencia (SP) and University of Torino (IT).

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 765274.

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