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  • Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.
  • We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.
  • Get robust compound data in human tissue models through our services. With proven pheno­typic assays in the OrganoPlate® platform, we support your drug discovery and development needs.
  • We offer several services to support your drug discovery and development needs. Find the overview here.
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  • Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.

  • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

  • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

  • Membrane-free microvascular formation and growth through an extracellular matrix (ECM).

  • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

  • OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.

  • Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs.

    Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, by our scientists.

  • Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.

  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
  • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
  • Any support questions about purchasing, products, or 3D tissue culture and analysis? Get in touch with our experts.
  • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

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EN

Therapeutic Developments and Innovative Strategies in Oncology: An Expert Discussion

Unravelling Oncology Therapeutics

Cancer continues to be a leading cause of mortality worldwide, accounting for nearly 10 million deaths in 2020. Alongside growing incidence rates each year, knowledge of molecular and tumor biology has also increased and notably affected cancer treatment paradigms. Until recently, cancer therapeutics focused on four main types of treatment: surgery, chemotherapy, radiotherapy, and targeted therapy. However, over the past ten years, immunotherapy has emerged as a novel and revolutionary approach to cancer treatment.

In this roundtable discussion, immuno-oncology decision-making experts from pharma, biotech, and academia will discuss the complexity of cancer and its diagnosis.The panel will also share their perspectives on current and future approaches towards cancer management and explore paradigm shifts surrounding immuno- and precision oncology.

Register here!


Key discussion points will include:

  • The complexity of cancer: the interplay between a tumor and its microenvironment
  • Current therapeutic approaches in oncology: their successes and failures
  • The role of the immune system in tumor growth of metastases
  • How to develop the best near-patient models in immuno-oncology
  • The most promising novel therapeutic approaches towards cancer

Watch and participate in this event live from the comfort of your home, office, or lab. At the end of the round table, there will be also an opportunity for the audience to ask questions during a live Q&A session.


The details

  • Date: Thursday, December 1st, 2022​​​​​​
  • Time: 10 AM -11 AM CET
  • Venue: Live stream at your (home) office

 

Meet the panel

Dr. Hans van Eenennaam, Ph.D.

Dr. van Eenennaam currently serves on the Board of Directors of Lygature, Catalym GmBH and ISD Immunotech AsP. After his tenure at Organon, Schering-Plough and MSD, he co-founded BioNovion in 2011 that was acquired by Aduro Inc. in 2015. Until 2019 he served as executive vice-president antibody research and site-head of Aduro Biotech Europe. Later that year he joined AIMM Therapeutics as chief scientific officer and is currently an independent consultant in biotechnology. Hans has a strong track record in developing novel therapies in immunology and immuno-oncology and is (co-)inventor of MK-5890 (anti-CD27), BION-1301 (anti-APRIL), ADU-1604 (anti-CTLA4) and ADU-1805 (anti-SIRPalpha).


 

Dr. Lukas Hawinkels, Ph.D

Dr. Hawinkels currently serves as the head of the research laboratory gastroenterology-hepatology and associate professor at the Dept of Gastroenterology-Hepatology at Leiden University Medical Center (LUMC). After obtaining his PhD degree at the LUMC-Gastroenterology department, he completed a post-doc project on the role of TGF-β (receptors) in cancer progression at the LUMC- department of molecular cell biology. In 2011 he was awarded a personal grant to start his independent research line on how interactions between cancer cells and CAFs influence metastatic spread. Lukas continued this research as an assistant professor at the Dept of Gastroenterology-Hepatology in 2015. Currently, his research team focuses on understanding how fibroblasts influence IBD and gastrointestinal cancers.


Jos Joore, Ph.D
Jos Joore is a biotech entrepreneur with over 30 years’ experience in bio-business and R&D. As co-CEO and co-founder of MIMETAS, Jos closed deals with most of the top-50 pharmaceutical companies, secured series A and B investment rounds, offering human organ-on-a-chip disease models for drug discovery and development. He is also co-founder and chairman of Pepscope, a company offering predictive drug testing based on endogenous kinase activity profiling in tissues using targeted mass spectrometry. Previously, he has held managerial positions in innovative biotech companies, including Pepscan, SkylineDx and Kreatech. Jos is co-author and co-inventor on over 50 peer-reviewed publications and patents. He holds a master’s degree in Biology, a Ph.D. in Developmental Biology and a master’s degree in Business Marketing.

 




Register for the Roundtable Discussion

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