• We offer tailored partnerships to support and transform drug discovery.

    Every collaboration is a bespoke arrangement, meticulously designed to discover new compounds and targets in patient relevant disease models.

  • MIMETAS offers flexible fee-for-service solutions for therapy prioritization, optimization, and de-risking of compounds.

    As an extension of your team, MIMETAS provides the expertise and resources needed for effective research and development.

  • Our OrganoReady program is made for you when you need optimized assays for investigational toxicology.

    We guarantee OrganoReady performance according to specifications, in a fast and convenient sales transaction with a clear fee structure.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.
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App Note: 3D Immune Cell Migration

Cell migration is an essential process for many biological phenomena such as early embryonic development and immune cell response. During inflammation, the recruitment and migration of T cells through the vascular system towards the site of inflammation is a crucial component.

In this app note, we demonstrate the development of an in vitro assay utilizing the OrganoPlate® platform to study T cell dynamics in combination with a blood vessel structure under perfused conditions, as well as the high-content imaging used to observe the migration of cells at various time points.

Benefits of the model:

  • Create complex cell migration assays that are easily scalable and compatible for high-content imaging
  • Perform quantitative assessment of immune cell dynamics, generating high throughput readouts such as cell numbers and cell migration distance


Download the app note here


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