MIMETAS Organ-on-a-Chip

Pancreatic cancer

3D pancreas tumors under increased interstitial fluid pressure are more chemoresistant

Blood vessels

Unique 3D vascular models that recapitulate hallmark features of human microvessels.

Kidney Proximal Tubule

Perfused human renal proximal tubule model

CNS Toxicity

Human iPSC-derived neurons in OrganoPlates® are electrically active, form networks and express mature neuronal markers. The models are used for screening, neurotoxicity assessment and many other applications.

Glomerulus

Glomerulus consisting of podocytes and glomerular endothele cells predict kidney failure

Blood brain barrier

Blood-brain barrier allows to investigate antibody transcytosis

Neuro-vascular unit

An in vitro grown neurovascular unit comprising neurons, astrocytes and a bloodvessel

Gut

OrganoPlate®-based intestinal models are membrane-free and closely mimic the in vivo gut epithelium.

Angiogenesis

Angiogenesis of perfused blood vessels in 3D

Human liver models

3D human liver models in the OrganoPlate^®

Culture optimization of breast cancer cell lines

Breast cancer therapy response

Investigating the use of OrganoPlate® technology in personalized medicine for drug selection and therapy response prediction for triple negative breast cancer.

Patient-derived glioma models

Development of a perfused organotypic human glioma model, ultimately aiming for personalized therapy selection.

Models

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Models

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