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      • Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.
    • Custom Model & Assay Development
      • We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.
    • Compound profiling & Screening
      • Get robust compound data in human tissue models through our services. With proven pheno­typic assays in the OrganoPlate® platform, we support your drug discovery and development needs.
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      • We offer several services to support your drug discovery and development needs. Find the overview here.
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    • Perfused Tubules
      • Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.

    • Cell-Cell Interactions
      • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

    • 3D Cell Migration
      • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

    • Angiogenesis
      • Membrane-free microvascular formation and growth through an extracellular matrix (ECM).

    • Vascularization
      • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

    • All Applications
      • OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.

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    • Knowledge Center
      • Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs.

        Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, by our scientists.

    • Publications
      • Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.

    • Case Studies
      • Get inspired by research done by our scientists, partners, and customers around the globe.

    • Blogs
      • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
    • Workshops & Trainings
      • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
    • Technical Support
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      • Frequently asked questions answered by our experts. Find here the answer you're looking for.
  • Knowledge Center
  • About Mimetas
  • Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.
  • We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.
  • Get robust compound data in human tissue models through our services. With proven pheno­typic assays in the OrganoPlate® platform, we support your drug discovery and development needs.
  • We offer several services to support your drug discovery and development needs. Find the overview here.
  • Start today with 3D tissue modeling
    Kickstart your first experiments with the OrganoPlate® through our OrganoStart packages.
  • OrganoFlow®
    Driving precisely-controlled perfusion flow in the OrganoPlate® platform

  • OrganoTEER®
    Enabling fast, automated, and impedance-based TEER measurements in OrganoPlate®. Assay 40 or 64 tissue culture chips with a few clicks, in less than two minutes.

  • Start today with 3D tissue modeling
    Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
  • OrganoPlate® is the solution for all in vitro tissue culture applications. Explore the entire OrganoPlate® family and its dedicated instruments here.

  • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

  • Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.

  • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

  • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

  • Membrane-free microvascular formation and growth through an extracellular matrix (ECM).

  • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

  • OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.

  • Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs.

    Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, by our scientists.

  • Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.

  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
  • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
  • Any support questions about purchasing, products, or 3D tissue culture and analysis? Get in touch with our experts.
  • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

  • Frequently asked questions answered by our experts. Find here the answer you're looking for.
  • Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.
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OrganoReady® Vascular Bed HUVEC

64 ready-to-use HUVEC vascular beds for your vascularization studies.

Are your in-vitro models lacking the key vascular component? With a pre-formed vascular bed, the OrganoReady® Vascular Bed HUVEC allows you to start your vascularization studies the right way: by introducing vasculature to your organoid and spheroid cultures. Save time by focusing on your grafting strategies while we produce and ship HUVEC vascular beds straight to your labs.

Built on the OrganoPlate® Graft, with 64 chips in parallel, you can immediately add your tissue of interest to the model and optimize conditions for vascularization of your tissue of interest. With this ready-to-use vascular bed, you can add another level of relevance to the models, as well as gain access to the core of the tissue explants.

OrganoReady Vascular Bed HUVEC features:

  • 64 pre-formed HUVEC vascular beds
  • Culture medium
  • Sprouting initiation mix: OrganoMedium HUVEC VB-I
  • Cell license included​
  • Prepared & fully quality controlled​
  • Ready for use after overnight recovery​

Assess and optimize the potential of your tissue of interest to form vascular connections with direct access to apical and basal compartments and access to your explanted tissue via the grafting chamber. Your tissue of interest can be inserted into the 1 mm circular grafting chamber against a validated batch of collagen-I and HUVEC vascular bed.

 

Our OrganoReady® Family

Product details

Meet the OrganoReady® Vascular Bed

 

Assess formation of lumenized and perfusable microvasculature
Easily p
erform a perfusion assay with dyes to determine interconnection through the vascular network and tissue.

We create the model so you can focus on your vascularisation studies
Preparation and QC of OrganoReady Vascular Bed HUVEC are done by our experts.

Quantify vascular remodelling events and tissue penetration via image analysis
Fully compatible with high-content imagers for analysing vessel intensity and dynamics.

Extract tissue sample for off-plate analysis
Sampling for off-plate analysis of RNA, DNA, proteins, and metabolites, or perform live-cell as well as fixed staining.

Get inspired by a wide range of applications
Conduct vascularization studies (spheroid, organoid,
tumeroid) for developing assays to assess cell migration, intravasation and killing. You can also create air liquid interface for lung or skin inflammation studies.

Apical and basal access to vasculature while tissue also remains accessible
Polarized and perfusable HUVEC microvasculature, facilitating drug transport and screens.

Request Quote

Want to know more?


Get up to speed with 3D tissue culture and learn how OrganoPlate® supports your research needs.

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