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    As an extension of your team, MIMETAS provides the expertise and resources needed for effective research and development.

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Phenotypic Disease Modeling for Immuno-Oncology: Putting Targets into Patient Context

On-demand Webinar

Modeling cancer with precision and accuracy requires the analysis of tumor modalities such as growth patterns, stromal shielding, vascularization, inflammation, mesenchymal transition, and metastasis. Organ-on-a-chip technology, such as the OrganoPlate® platform, may recapitulate the tumor microenvironment (TME) in vitro, offering unparalleled detail and human relevance in a 3D environment. Developing complex in vitro cancer models, that closely mimic this multi-faceted disease, is pivotal in improving cancer drug discovery and establishing more effective treatments for patients.

Novel and recently approved drugs, such as T-cell engagers and checkpoint inhibitors, indicate the principal role of the immune system in cancer. Teasing apart the intricate and dynamic interactions between cancer cells, immune cells and the surrounding tumor tissue is a critical step in gaining a better understanding of the immune system’s role in the disease.

Watch our on-demand webinar with Henriëtte Lanz, PhD (Vice President Biology at MIMETAS). Dive deep into MIMETAS’ expertise in disease modeling and drug screening within the field of immuno-oncology. The webinar explores, among other topics, the immuno-suppressive and stimulatory nature of the tumor microenvironment (TME) in hepatocellular carcinoma.

Key topics include:

  • Comprehensive in vitro modeling of the TME
  • The interplay between angiogenesis, stroma and immune infiltrate
  • The influence of different parameters of the TME on the response to Standard of Care
  • The benefits of partnering with MIMETAS to accelerate your research and improve predictive responses to conventional and targeted therapies

 

Access the recording here

 


Speaker

 

Henriette Lanz, PhD is Vice President Biology at MIMETAS. She studied Life, Science and Technology during both her bachelor and master degrees, before conducting her PhD research on cancer-related targets sensed by apoptin, a tumor-selective apoptosis inducing protein, at Leiden University. At MIMETAS, she oversees the Model Development Department, being part of various types of internal and external projects.

 

 

 

 

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