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      • Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.
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      • We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.
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      • Get robust compound data in human tissue models through our services. With proven pheno­typic assays in the OrganoPlate® platform, we support your drug discovery and development needs.
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      • We offer several services to support your drug discovery and development needs. Find the overview here.
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    • Perfused Tubules

      • Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.

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      • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

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      • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

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      • Membrane-free microvascular formation and growth through an extracellular matrix (ECM).

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      • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

    • All Applications

      • OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.

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    • Knowledge Center

      • Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs.

        Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, by our scientists.

    • Publications

      • Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.

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      • Get inspired by research done by our scientists, partners, and customers around the globe.

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      • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
    • Workshops & Trainings
      • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
    • Technical Support
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      • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

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      • Frequently asked questions answered by our experts. Find here the answer you're looking for.
  • Knowledge Center
  • About Mimetas
  • Expand your drug discovery capacity, shoulder to shoulder with our scientific team. Proprietary human disease biology in the OrganoPlate® platform. Together we make the therapeutics of tomorrow.
  • We create novel human tissue and disease models in the OrganoPlate® platform. Our experts are looking forward to developing assays according to your specifications.
  • Get robust compound data in human tissue models through our services. With proven pheno­typic assays in the OrganoPlate® platform, we support your drug discovery and development needs.
  • We offer several services to support your drug discovery and development needs. Find the overview here.
  • Start today with 3D tissue modeling
    Kickstart your first experiments with the OrganoPlate® through our OrganoStart packages.

  • OrganoFlow®
    Driving precisely-controlled perfusion flow in the OrganoPlate® platform

  • OrganoTEER®
    Enabling fast, automated, and impedance-based TEER measurements in OrganoPlate®. Assay 40 or 64 tissue culture chips with a few clicks, in less than two minutes.

  • Start today with 3D tissue modeling
    Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.

  • OrganoPlate® is the solution for all in vitro tissue culture applications. Explore the entire OrganoPlate® family and its dedicated instruments here.

  • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

  • Layered tissues with perfused tubules in the absence of artificial membranes form the heart of our permeability and transport science. Study cell interactions, permeability, absorption, transport, and transcytosis without physical barriers.

  • Co-culture layered & structured tissues without artificial membranes with perfect imaging, to study barrier-free cellular interactions, cell-cell signaling, and migration.

  • Evaluate the effect of chemotactic triggers or cells on the migration of cells through an extracellular matrix.

  • Membrane-free microvascular formation and growth through an extracellular matrix (ECM).

  • The missing link in tissue culture: add perfusable human vasculature to your tissue models, and recreate sophisticated microenvironments with OrganoPlate® Graft.

  • OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment. Find the overview of applications here.

  • Visit our Knowledge Center to get up to speed with 3D tissue culture and to learn how OrganoPlate® supports your research needs.

    Read our publications, application notes, watch our webinars, or check out the supporting protocols and brochures. All compiled for you, by our scientists.

  • Get inspired by peer-reviewed publications of our scientists, partners, and customers around the globe.

  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.
  • Kickstart your experiments with the most sophisticated 3D tissue culture platform. Find out which training fits your 3D tissue modeling needs best.
  • Any support questions about purchasing, products, or 3D tissue culture and analysis? Get in touch with our experts.

  • Thinking of using OrganoPlate for your research? Request a quote for the product(s) of your interest.

  • Frequently asked questions answered by our experts. Find here the answer you're looking for.
  • Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.
EN

Webinar: The Future of 3D in vitro Models: How Organs-on-chips benefit from Imaging on Multimode Plate Readers

On-demand Webinar

High content imaging has become the most commonly used readout for 3D tissue and disease models in microphysiological systems. However, the temporal resolution of automated high content imagers is limited, rendering them inadequate for certain applications. We employed the OrganoPlate®, a standardized and high-throughput capable organ-on-chip platform, in conjunction with the Tecan Spark® Cyto multimode plate reader in an assay to investigate the toxic effect of snake venom on endothelial tubules grown in the chip. Several readouts were utilized to gain insights on the action of the venom of six different snake species.

In this webinar, you will:

  • Discover the high throughput of the OrganoPlate platform and its compatibility with multimode plate readers.
  • Learn how we utilized the Spark Cyto multimode reader to combine excellent temporal resolution with intermittent highresolution imaging for improved morphological insights.
  • Explore technical aspects of extracting data from the OrganoPlate using a multimode reader and how it can enhance your toxicity related research.

 

Disclaimer: Spark® Cyto is for Research Use Only. Not for use in diagnostic procedures.

Register here

Speakers

Dr. Christian Oberdanner is an Application Scientist at Tecan Austria. He studied molecular biology at the University of Slazburg, with a strong focus on cell and tumor biology. Christian started working for Tecan Austria as an external scientific consultant in 2005 and joined the company permanently in 2006. Since then, he has held several roles, including Application Scientist, Application Specialist and Product Manager. Christian's priorities within Tecan are multimode microplate reader applications and cell imaging.

 


Flavio Bonanini is a Marie Sklodowska-Curie fellow at the PoLiMeR consortium and Early Stage Researcher affiliated with MIMETAS. Previously, he studied biology and biomedical engineering, specializing in tissue engineering at the Swiss Federal Institute of Technology (ETH) in Zurich. In his current role, he focuses on establishing and developing liver models in the OrganoPlate, MIMETAS high throughput organ-on-chip platform.

 

 

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